Assistant Professor Vanderbilt University Nashville, Tennessee
Abstract: Background / Significance: Catatonia is increasingly recognized in critically ill patients, however risk factors for its development remain unclear. Clinical literature as well as theoretical models suggest that antipsychotic exposure may potentiate or worsen catatonia in certain patient populations due to dopamine blockade, however to the best of our knowledge no studies have explored this systematically. We hypothesize that exposure and cumulative dose of antipsychotics is associated with less days alive and free from catatonia in the Intensive Care Unit (ICU).
